%T Differential Elastic Image Registration %A Senthil Periaswamy %A Hany Farid %R Technical Report TR2001-413 %I Dartmouth College, Computer Science %C Hanover, NH %D September 2001 %U http://www.cs.dartmouth.edu/reports/TR2001-413.ps.Z %X We have applied techniques from differential motion estimation to the problem of automatic elastic registration of medical images. This method models the mapping between images as a locally affine but globally smooth warp. The mapping also explicitly accounts for variations in image intensities. This approach is simple and highly effective across a broad range of medical images. We show the efficacy of this approach on several synthetic and clinical images.