BIB-VERSION:: CS-TR-v2.0 ID:: ncstrl.dartmouthcs//TR2002-431 ENTRY:: May 30, 2002 ORGANIZATION:: Dartmouth College, Computer Science TITLE:: Analysis of Protein Sequences Using Time Frequency and Kolmogorov-Smirnov Methods TYPE:: Technical Report (paper) REVISION:: 3 AUTHOR:: Essien, Kobby RETRIEVAL:: For a paper copy, email RETRIEVAL:: For a paper copy, write to Technical Report Librarian Department of Computer Science Dartmouth College 6211 Sudikoff Laboratory Hanover, NH 03755-3510 USA RETRIEVAL:: Compressed Postscript at http://www.cs.dartmouth.edu/reports/TR2002-431.ps.Z RETRIEVAL:: PDF at http://www.cs.dartmouth.edu/reports/TR2002-431.pdf DATE:: May 2002 ABSTRACT:: The plethora of genomic data currently available has resulted in a search for new algorithms and analysis techniques to interpret genomic data. In this two-fold study we explore techniques for locating critical amino acid residues in protein sequences and for estimating the similarity between proteins. We demonstrate the use of the Short-Time Fourier Transform and the Continuous Wavelet Transform together with amino acid hydrophobicity in locating important amino acid domains in proteins and also show that the Kolmogorov-Smirnov statistic can be used as a metric of protein similarity. NOTE:: Senior Honors Thesis. Advisor: Metin Akay.
END:: ncstrl.dartmouthcs//TR2002-431