Current lab members

  • Chris Bailey-Kellogg
  • Himanshu Chandola
  • Yoonjoo Choi
  • Lu He
  • Betty Huang
  • Andrew Scott Parker
  • Tuobin Wang

Highlighted projects

  • deimmunization
  • graphical models
  • oligomer
  • recombination
  • multimodal
  • nmr

On sabbatical academic year 2011-2012.

Recent papers

  • Algorithms for optimizing cross-overs in DNA shuffling
  • NMR structural inference of symmetric homo-oligomers
  • A graphical method for analyzing distance restraints for structure determination of symmetric protein homo-oligomers
  • Optimization of therapeutic proteins to delete T-cell epitopes while maintaining beneficial residue interactions
  • Optimization of combinatorial mutagenesis
  • Accounting for conformational entropy in predicting binding free energies of protein-protein interactions

[more...]

News

Jan 12Postdoc position available for the newly-funded antibody effector function project (Gates Foundation Collaboration for AIDS Vaccine Discovery)
Jan 12Welcome to Dr. Yoonjoo Choi, who is joining us as a postdoc after completing a DPhil in protein informatics with Charlotte Deane at Oxford
Dec 11Congratulations to Lu, whose paper "Ballast: A Ball-based Algorithm for Structural Motifs" has been accepted to RECOMB-2012
Dec 11Congratulations to Andrew, whose paper "Structure-Guided Deimmunization of Therapeutic Proteins" has been accepted to RECOMB-2012
Dec 11Congratulations to Andrew, who was invited to give an oral presentation "Optimization algorithms for the design of immunotolerant biotherapies" at the 243rd ACS National meeting

[more...]

Contact

cbk -at- cs -dot- dartmouth -dot- edu
Sudikoff Lab (Maynard & College), room 250
603-646-3385