The lab has a fun group of very talented students working on a variety of projects from a variety of perspectives. You can see some short descriptions of our current research themes, and read some of our papers. We also enjoy the quality of life in the area. Here are some pictures from a "typical" group meeting (Xiaoduan leading a discussion of a paper, on top of nearby Mt. Cardigan): image 1; image 2; image 3.

Current Lab Members

Graduate students

Undergraduate students

  • Nan Zheng (Presidential Scholar, Fall 2009 / Winter 2010; WISP intern, winter/spring 2008)
    Visualization of residue coupling motifs

Alumni

Postdocs

PhD students

  • Shobha Potluri (2007)
    Thesis: "Complete Configuration Space Analysis for Structure Determination of Symmetric Homo-oligomers by NMR".
    On to a postdoc at Pfizer Global Research.
  • John Thomas (2009)
    Thesis: "Graphical Models of Sequence Constraints on Protein Families".
    On to employment at Crimson Hexagon.
  • Olga Vitek (Purdue statistics 2005)
    Thesis: "An inferential approach to protein backbone nuclear magnetic resonance assignment".
    On to a postdoc with Dr. Ruedi Aebersold, and then a faculty position in Statistics and CS at Purdue.
  • Xiaoduan Ye (2007)
    Thesis: "Experiment planning for protein structure elucidation and site-directed protein recombination".
    On to employment at Bloomberg.

MS students

  • David Callender
    Data mining for pandemic preparedness
  • Sheetal Chainraj (Purdue 2004)
    Random graph algorithms for automated assignment in NMR.
    On to employment at Bloomberg.
  • Jairav Desai
    Robotic assembly of chimaeric libraries
  • Hetu Kamisetty (Purdue 2005)
    Graph algorithms and pattern recognition in NMR. On to the PhD program at CMU.
  • Jiangtian Li (Purdue industrial engineering 2004) Computation, analysis, and optimization of free energies of association for serine proteinase inhibitors.
    On to the PhD program at NCSU.

Undergraduate students

  • Noah Benson (Purdue 2005; Hughes bioinformatics fellow)
    Graph analysis and algorithms for NOESY-based NMR automated assignment.
    On to graduate studies in computational biology at the University of Washington.
  • Megan Crapster (WISP intern, spring/summer 2006)
    Target identification for protein complex determination.
  • Mark Henle (Presidential Scholar, 2005)
    Algorithms in protein engineering by recombination.
  • Aly Azeem Khan (Purdue 2004; Hughes bioinformatics fellow)
    Computational modeling of protein structure, flexibility, and complexes for model discrimination via cross-linking and mass spectrometry.
    On to graduate studies in computational biology at CMU.
  • Kyle Krull (Purdue 2003)
    Computational modeling of protein-protein interactions for design of enzyme inhibitors.
    On to graduate studies in biochemistry / molecular biology at Purdue.
  • Melissa Lokensgard (WISP intern, winter/summer 2007)
    Solution scattering for protein complexes
  • Jeff Milloy (honors thesis, 2009)
    Accelerating mass spectrometry proteomics studies
  • Grace Nauman (WISP intern, winter/summer 2009)
    Correlated mutations in HIV-1 protease.
  • Karlam Ng (Purdue 2003)
    Algorithms for classification of amino acid type from NMR data.
    On to graduate studies in CS at Stanford.
  • Liz Saftalov (Purdue 2005; Ruzicka fellow)
    Algorithms in protein engineering by recombination.
    On to graduate studies in psychology at Purdue.
  • Chetak Sirsat (Purdue 2004; Hughes bioinformatics fellow)
    Algorithms for interpretation of mass spectral data under intra- and inter-molecular cross-linking.
    On to graduate studies in computational biology at Purdue.
  • Mike Stoppelman (Purdue 2004)
    Bridging the molecular-cellular modeling divide.
    On to employment at Google.
  • Shelley Weaver (WISP intern, winter/spring 2006)
    Robotic combinatorial construction of chimaeric genes.
  • Jeremy Warburg (Dartmouth 2008)
    Visualization of residue coupling motifs
  • Tim Williamson (Purdue 2005; Hughes fellow)
    Solution scattering for protein structure discrimination.
    On to the MS program in Computational Life Sciences at Purdue.
  • Isaura Zelaya (Dartmouth 2008; WISP intern)
    Protein-protein interactions.

Collaborators

Our research is highly collaborative, and we're very lucky to be working with great researchers.