Current lab members

  • Chris Bailey-Kellogg
  • Andrew O'Laughlin
  • Bowen Dai
  • Daniel Mattox
  • Natalia Syzochenko
  • ~Neerja Thakkar
  • Srivamshi Pittala

Highlighted projects

  • deimmunization
  • antibody effector functions
  • MHC:peptide:TCR
  • graphical models
  • recombination
  • oligomer

Current/upcoming classes

2018-19 academic year: Research leave

Recent papers

  • Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV
  • Pareto optimization of combinatorial mutagenesis libraries
  • DisruPPI: Structure-based computational redesign algorithm for protein binding disruption
  • High-resolution definition of humoral immune response correlates of effective immunity against HIV
  • Computationally-driven identification of antibody epitopes
  • Computationally optimized deimmunization libraries yield highly mutated enzymes with low immunogenicity and enhanced activity

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News

Sep 18Congratulations to Srivamshi, along with collaborators in Margie Ackerman's lab and Galit Alter's lab and others, for a Nature Medicine paper appearing today: "Route of immunization defines multiple mechanisms of vaccine-mediated protection against SIV"
Aug 18Congratulations to Daniel, who was awarded a Burroughs Wellcome Fund: Big Data in the Life Sciences fellowship
Aug 18Congratulations to Arij Elfaki and Sahaj Shah, who were awarded Sophomore Science Scholarships to do research with us this year

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Contact

cbk -at- cs -dot- dartmouth -dot- edu
6211 Sudikoff Lab, Hanover, NH 03755, USA
Sudikoff Lab (corner of Maynard & College), room 250
603-646-3385